I’m opting for something a little bit more specific for this edition of Featured Journal, along with something I have a personal interest in – Organometallics.
Although Organometallic chemistry might seem like a very specific topic, it has a vast variety of applications, such as catalysis, biomimicry, materials science and solid-state chemistry. It may seem a relatively new area of chemistry, but it has rapidly developed over the years, and has great value amongst the chemical sciences.
With an impact factor of 4.145, Organometallics features articles, communications, mini-reviews, and notes on all aspects of organometallic chemistry, making it a great read for anyone interested in this area. This is a deceptive journal which offers a much bigger variety and richness of chemistry than you might expect.
You can find the latest issue of Organometallics here.
In Organometallics today:
“Reactions of Al-P Based Frustrated Lewis Pairs with Carbonyl Compounds”
Frustrated Lewis Pairs are becoming an increasingly popular topic, with many compounds containing this relatively new motif showing interesting and unexpected reactivity. Frustrated Lewis Pairs contain Lewis acidic and Lewis basic centres which are separated in some way, either by a rigid backbone in the molecule, or bulky substituents. This means that they’re unable to form an adduct, causing the pair to be ‘frustrated’. This often leads to interesting reactivity, and this paper reports the reactions of aluminium and phosphorus-based frustrated Lewis Pairs with carbonyl compounds. Variations in the carbonyl compound used led to different reactivity, with the promise of some exciting applications in the future. This is worth keeping an eye on!
“β-Diketiminate Derivatives of Alkali Metals and Uranium”
I couldn’t feature this journal without highlighting a paper from my own University! Unlike transition metal chemistry, the chemistry of Uranium and its neighbours is relatively underdeveloped, and this paper describes the use of the popular β-Diketiminate ligand type to stabilise a series of uranium compounds. A particularly unusual example is an inverse sandwich complex, with a molecule of benzene binding to two uranium centres. These compounds have been shown to have interesting properties, with a previous example by the same authors showing single-molecule magnetism. It’s a very cool compound indeed!
“An Efficient Catalyst Based on Manganese Salen for Hydrosilylation of Carbonyl Compounds”
Hydrosilation is an important class of reaction, which can be used as a milder alternative to such as hydrogenation. It provides an atom-efficient, gentle route from carbonyl to hydroxyl groups, and so is important for organic synthesis. Efficient catalysts for this processes are highly desirable, especially if derived from environmentally-friendly and abundant metal centres. You might have seen manganese salen compounds used in catalysis before, but this is a new application for this kind of complex. The catalyst was very effective at low-loading, and effectively catalysed the reaction with good functional group tolerance, showing great potential in compounds of this type for catalysts in this and similar processes.
“A Phosphorescent Rhenium(I) Tricarbonyl Polypyridine Complex Appended with a Fructose Pendant That Exhibits Photocytotoxicity and Enhanced Uptake by Breast Cancer Cells”
Obviously, effective anti-cancer agents are incredibly important research topic in all areas of chemistry, and efforts are continually being made to synthesise these compounds. Here, the authors report the use of a phosphorescent polypyridyl rhenium(I) compound for effective imaging of breast cancer cells. The use of a fructose moiety in the compound allowed for selective uptake into breast cancer cells over other cancer cells and healthy cells, highlighting the effectiveness of the complex for this particular use. This is an intriguing development in this field, and could be very useful in the future of anti-cancer treatment.
As you can see, Organometallics contains a great variety of areas of chemistry under one roof, and so provides an interest to researchers from many different chemical backgrounds. Organometallic compounds have both a fundamental and practical interest, and this is a topic which will continue to grow and flourish as the needs of the chemical community change with time. Always interesting, always varied, it’s always worth a read.